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Iodine Status Linked to Psychomotor Development in Children

In a study involving 86 children who were assessed via the Bayley Scale of Infant Development at 12, 18, and 24 months, maternal serum free thyroxine (FT(4)) levels during the first trimester of pregnancy were found to be the major determinant of psychomotor development at 18 and 24 months. Children of mothers with serum free thyroxine levels less than the 25th percentile (<10 pg/mL) were found to have an OR of 2.1 for mild to severe delay, and alterations in behavior were observed at 12 months and related to subsequent changes in development. The authors conclude, "This study highlights the need to implement active measures of iodine supplementation periconceptionally and during pregnancy and lactation because the negative effects on development and behavior might be prevented through preemptive action."


"Psychomotor Development of Children from an Iodine-Deficient Region," Costeira MJ, Oliveira P, et al, J Pediatr, 2011 April 12; [Epub ahead of print]. (Address: Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal).

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