Alternative Health Blog
Vitamin D Status, in African Americans and Progression of Kidney Disease
In a study involving data collected from 13,328 subjects, 34% of non-Hispanic black subjects were found to have low vitamin D status (25(OH)D < 15 ng/ml), as compared to 5% of non-Hispanic white subjects. Over the course of 9.1 years, 65 subjects were found to develop end stage renal disease (ESRD). After adjusting for various potential confounders, subjects with 25(OH)D < 15 ng/ml were found to have a 2.6-fold greater incidence of ESRD, as compared to those with levels >/=15 ng/ml (incidence rate ratio: 2.64). After adjusting for various clinical covariates but not 25(OH)D, Black subjects were found to have a 2.83-fold higher risk for developing ESRD, as compared to white subjects, and after adjusting for 25(OH)D levels, this reduced the risk by 58%. The authors conclude, “Low 25(OH)D levels may account for a substantial proportion of the increased risk for ESRD experienced by black individuals.”
Reference:
“25-Hydroxyvitamin D Levels, Race, and the Progression of Kidney Disease,” Melamed ML, Astor B, et al, J Am Soc Nephrol, 2009 Oct 29
Reference:
“25-Hydroxyvitamin D Levels, Race, and the Progression of Kidney Disease,” Melamed ML, Astor B, et al, J Am Soc Nephrol, 2009 Oct 29
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