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Higher Levels of Vitamin D May Be Associated with a Lower Risk of Lung Cancer in Women and Younger Subjects


In a prospective study involving 6,937 men and women, higher levels of vitamin D were associated with a significantly lower risk of lung cancer in women and younger participants. During a maximum follow-up of 24 years, 122 cases of lung cancer were identified. After adjusting for potential confounders, higher serum 25-hydroxyvitamin D levels were associated with reduced risk of lung cancer risk in women (84% reduced risk) and younger participants (66% reduced risk). No association was observed between vitamin D status and lung cancer risk in men and older participants. Thus, the authors of this study conclude, "…although there was no overall association between vitamin D and lung cancer risk, women and young participants with a higher level of vitamin D were observed to have a lower lung cancer risk.
 
Reference:
"Vitamin D status and the risk of lung cancer: a cohort study in Finland," Kilkkinen A, Knekt P, et al, Cancer Epidemiol Biomarkers Prev, 2008; 17(11): 3274-8.



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