| We welcome Alternative Health Journal Members to the Insiders Health Family |
|
Ipriflavone
Ipriflavone is a synthetic flavonoid (isoflavone) derived from the soy compound daidzein.
Where is it found?
Ipriflavone does occur naturally in food but only in trace amounts. It is available as a nutritional supplement.
Ipriflavone has been used in connection with the following conditions (refer to the individual health concern for complete information):
| Science Ratings | Health Concerns |
|---|---|
 |
Osteoporosis |
 Reliable
and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies
suggesting a health benefit or minimal health benefit. For an herb, supported by traditional use but minimal
or no scientific evidence. For a supplement, little scientific support and/or minimal health
benefit. |
|
Who is likely to be deficient?
As ipriflavone is not an essential nutrient, no deficiency state exists.
How much is usually taken?
The typical supplemental amount of ipriflavone is 200 mg three times daily. Taking 300 mg twice daily has been reported to be just as effective as 200 mg three times per day.1
Are there any side effects or interactions?
In a trial of ipriflavone for osteoporosis, 29 of the 132 women in the ipriflavone group completing the three-year trial developed a clinically significant drop in lymphocytes.2 These cells, which make up approximately 22 to 28% of the white blood cells in the normal adult, are critical components of the immune system and its ability to respond to viral infections. In some of these women, a return to normal levels took almost two years after they had stopped the ipriflavone. Since this finding has been reported in one other smaller clinical trial,3 it suggests that women choosing to take ipriflavone should have their lymphocytes measured regularly by their doctor.
In double-blind studies, the frequency of perceived side effects in ipriflavone-treated people (14.5%) was actually less than that observed in people receiving the placebo (16.1%).4 Side effects were mainly mild stomach upset. Researchers recommend that patients with severe kidney disease take a lower amount of ipriflavone (200 to 400 mg daily).5
Are there any drug
interactions?
Certain medicines may interact with ipriflavone. Refer to drug interactions for a list of those medicines.
References
(To view, roll mouse over the "References" heading; to hide, click on the heading)
Copyright © 2007 Healthnotes, Inc. All rights reserved. www.healthnotes.com
Learn more about Healthnotes, the company.
Learn more about the authors of Healthnotes.
The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires September 2008.