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Vitamin E Supplementation May Reduce the Risk of Chronic Lung Disease in Women

In a study involving 38,597 women enrolled in the Women's Health Study (WHS), a randomized, double-blind, placebo-controlled, factorial trial of vitamin E (600 IU every other day) and aspirin (100 mg every other day), results indicate that vitamin E supplementation may be associated with a reduced risk of chronic lung disease. During 10 years of follow-up of women in the vitamin E and placebo groups, 760 first occurrences of chronic lung disease were reported in the vitamin E group compared with 846 in the placebo group. Using Cox proportional hazards models adjusted for confounders, supplementation with vitamin E was associated with a 10% reduced risk of chronic lung cancer. Thus, the authors of this study conclude, "In this large randomised trial, assignment to 600 IU vitamin E led to a 10% reduction in the risk of chronic lung disease in women.

Reference:

"Randomised vitamin E supplementation and risk of chronic lung disease in the Women's Health Study," Agler AH, Cassano PA, et al, Thorax, 2011 Jan 21; [Epub ahead of print]. (Address: Division of Nutritional Sciences, Cornell University, Ithaca, New York, USA).

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