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Vitamin D Deficiency May Be Associated With Cognitive Impairment in Elderly Women

In a cross-sectional, population-based study involving 752 women aged 75 years or more, results indicate that vitamin D deficiency may be associated with cognitive impairment. The patients were categorized as vitamin D deficient (< 10 ng/mL; n=129) or non-deficient (>/= 10 ng/mL; n=623). Cognitive impairment was defined as a Pfeiffer Short Portable Mental State Questionnaire (SPMSQ) score <8. Vitamin D deficient women had a lower mean SPMSQ score, and more often had an SPMSQ score <8, compared with non-deficient women. Additionally, after adjusting for confounders, serum 25(OH)D deficiency was associated with cognitive impairment (OR=1.99). Thus, the authors of this study conclude, “25-Hydroxyvitamin D deficiency was associated with cognitive impairment in this cohort of community-dwelling older women.”
 
Reference:
“Association of vitamin D deficiency with cognitive impairment in older women. Cross-sectional study,” Annweiler C, Beauchet O, et al, Neurology, 2009 Sep 30;
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June 19, 2008
Derrick DeSilva Jr., M.D.
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Dr. Derrick DeSilva is on the Attending Staff at the Raritan Bay Medical Center in Perth Amboy, N.J., and on the teaching faculty at JFK Medical Center in Edison, N.J.

He has lectured on various topics in medicine --nationally and internationally-- and has his own talk show called Ask the Doctor which airs on WCTC in New Jersey (1450 AM) as well as his own television show, "To Your ...