Alternative Health Blog
Vitamin B6 Supplementation May Improve Inflammatory Responses in Patients With Rheumatoid Arthritis
In a randomized, controlled study involving 35 patients with
rheumatoid arthritis (RA), results indicate that supplementation
with vitamin B6 may exert a beneficial effect on inflammatory
responses. The patients were randomized to 5 mg/day folic acid
(control group, n=15) or 5 mg/day folic acid + 100 mg/day vitamin
B6, for a period of 12 weeks. At intervention end, significant
decreases in plasma IL-6 and TNF-alpha levels were observed in the
vitamin B6 group. Thus, the authors of this study conclude, "A
large dose of vitamin B(6) supplementation (100 mg/day) suppressed
pro-inflammatory cytokines (that is, IL-6 and TNF-alpha) in
patients with RA."
Reference: "Vitamin B(6) supplementation improves
pro-inflammatory responses in patients with rheumatoid arthritis,"
Huang SC, Huang YC, et al, Eur J Clin Nutr, 2010 Jun 23; [Epub
ahead of print]. (Address: School of Nutrition, Chung Shan Medical
University, Taichung, Taiwan).