Alternative Health Blog

In a controlled study involving 15 healthy subjects, results indicate that long-term supplementation with EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) may decrease the risk of calcium oxalate stone formation. After a control phase (subjects consumed a standardized diet for 5 days) the subjects consumed a free diet while receiving supplementation with 900 mg EPA and 600 mg DHA, for a period of 30 days. At intervention end, relative supersaturation with calcium oxalate decreased significantly (23%) due to significantly decreased urinary oxalate excretion. Thus, the authors of this study conclude, "Results show that 30-day n-3 fatty acid supplementation effectively decreases urinary oxalate excretion and the risk of calcium oxalate crystallization."