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Probiotics Supplementation In Relieving Symptoms of Rheumatoid Arthritis

In a randomized, double-blind, placebo-controlled, parallel-design study involving 45 adults with symptoms of rheumatoid arthritis (RA) receiving treatment with pharmacological anti-arthritic medications, results indicate that adjuvant supplementation with lactic acid-producing bacteria (LAB) probiotics may exert beneficial effects. The subjects were randomized to receive LAB probiotic preparation, Bacillus coagulans GBI-30, 6086, or placebo daily for a period of 60 days. Subjects in the probiotic-supplemented group reported improvement in the Patient Pain Assessment score and Pain Scale, and greater improvement in patient global assessment and self-assessed disability, and ability to walk 2 miles, reach, and participate in daily activities, compared to subjects in the placebo group. Thus, the authors conclude, "Results of this pilot study suggest that adjunctive treatment with Bacillus coagulans GBI-30, 6086 LAB probiotic appeared to be safe and effective for patient s suffering from RA. Because of the low study population size, larger trials are needed to verify these results."   Reference: "Bacillus coagulans: a viable adjunct therapy for relieving symptoms of rheumatoid arthritis according to a randomized, controlled trial," Mandel DR, Holmes J, et al, BMC Complement Altern Med, 2010 Jan 12; [Epub ahead of print]. (Address: David R. Mandel, MD, Inc., Mayfield Village, OH 44143, USA. E-mail: david@dmandelmd.com ).
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Contributor Since:
June 19, 2008
Derrick DeSilva Jr., M.D.
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Dr. Derrick DeSilva is on the Attending Staff at the Raritan Bay Medical Center in Perth Amboy, N.J., and on the teaching faculty at JFK Medical Center in Edison, N.J.

He has lectured o...