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Probiotics May Reduce the Risk of Clostridium difficile-associated Disease in Critically Ill Patients
In a study involving 22 ICU patients being treated with antibiotics, supplementation with the probiotic, Lactobacillus plantarum 299v (given in the form of fermented oatmeal gruel) was found to reduce colonization with Clostridium difficile. 19% of patients who were not given the probiotic-rich gruel were found to have colonization with C. difficile, while none of the patients treated with probiotics were found to be colonized with C. difficile. Given the high risk of Clostridium difficile-associated disease (CDAD) in hospitalized patients treated with antibiotics, these results are promising, suggesting that probiotics offer an effective way of reducing the risk of CDAD in this population of patients.
Reference:
"Lactobacillus plantarum 299v reduces colonisation of Clostridium difficile in critically ill patients treated with antibiotics," Klarin B, Wullt M, et al, Acta Anaesthesiol Scand, 2008; 52(8): 1096-102
Reference:
"Lactobacillus plantarum 299v reduces colonisation of Clostridium difficile in critically ill patients treated with antibiotics," Klarin B, Wullt M, et al, Acta Anaesthesiol Scand, 2008; 52(8): 1096-102
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Dr. Derrick DeSilva is on the Attending Staff at the Raritan Bay Medical Center in Perth Amboy, N.J., and on the teaching faculty at JFK Medical Center in Edison, N.J.
He has lectured on various topics in medicine --nationally and internationally-- and has his own talk show called Ask the Doctor which airs on WCTC in New Jersey (1450 AM) as well as his own television show, "To Your ...
He has lectured on various topics in medicine --nationally and internationally-- and has his own talk show called Ask the Doctor which airs on WCTC in New Jersey (1450 AM) as well as his own television show, "To Your ...
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