Alternative Health Blog
Probiotic Supplementation Prior to Surgery May Benefit Patients Undergoing Colorectal Cancer Resection Surgery
In a randomized study involving 60 patients with colorectal cancer, oral supplementation with viable bifidobacterium prior to surgery was found to be associated with improvements in bacterial dysbiosis, immunity, intestinal flora, and reductions in post-operative infections, as compared to subjects who received routine enteral nutrition. Subjects in the treatment group were found to have fewer postoperative septic complications, as compared to subjects in the control group. The ratio of bifidobacterium/E-coli (B/E) was found to be significantly decreased in the treatment group postoperatively, as compared to pre-operatively (2.01 vs. 26.53). Stool SIgA was found to be higher in the treatment group 9 days post-operation, while serum IgG, IgM, IgA, IL-6, and CRP were found to be lower in the treatment group, versus the control group. These results suggest that patients with colorectal cancer undergoing resection may benefit from supplementation with bifidobacterium probiotics prior to surgery.
"[Effect of viable bifidobacterium supplement on the immune status and inflammatory response in patients undergoing resection for colorectal cancer]," Zhang JW, Du P, et al, Zhonghua Wei Chang Wai Ke Za Zhi, 2010 Jan; 13(1): 40-3.