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Omega-3 Fatty Acid Supplementation Reduces Depression in Elderly
By Derrick DeSilva Jr., M.D., Community Insider -- Published: February 22, 2011

In a randomized, double-blind, placebo-controlled, 2-month trial involving 46 elderly depressed females (aged 66-95 years), treatment with omega-3 long-chain polyunsaturated fatty acids (2.5 g/d, containing 1.67 g EPA and 0.83 g DHA) was found to significantly reduce scores on the Geriatric Depression Scale and significantly improve physical and mental components of the SF-36, after a period of 2 months, in the intervention group alone. The authors conclude, "The supplementation of omega-3 LCPUFA in elderly female patients reduces the occurrence of depressive symptoms, improves phospholipids fatty acids profile and health-related quality of life."

Reference:

"Long chain omega 3 polyunsaturated Fatty acids supplementation in the treatment of elderly depression: effects on depressive symptoms, on phospholipids Fatty acids profile and on health-related quality of life," Rondanelli M, Giacosa A, et al, J Nutr Health Aging, 2011; 15(11): 37-44. (Address: M. Rondanelli, Department of Applied Health Sciences, Section of Human Nutrition and Dietetics, Faculty of Medicine, Azienda di Servizi alla Persona di Pavia, University of Pavia Istituto di Cura Santa Margherita, Via Emilia 32, 27100 Pavia, Italy. E-mails: serv.nutrizione@asppavia.it and mariangela.rondanelli@unipv.it ).
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