Alternative Health Blog

Natural Dietary Supplements Improve Function and Decrease Alzheimer's disease Neuropathology

By Derrick DeSilva Jr., M.D., Community Insider -- Published: December 21, 2010

In a study involving a mouse model of Alzheimer's disease, administration of a 'medical food cocktail' containing curcumin, piperine, epigallocatechin gallate, alpha-lipoic acid, N-acetylcysteine, B vitamins, vitamin C, and folate, for a period of 6 months, was found to improve learning and memory (cortical- and hippocampal- dependent learning) and decrease soluble amyloid-beta, including amyloid-beta oligomers, suggesting that, "...combination diet consisting of natural dietary supplements improves cognitive functioning while decreasing AD neuropathology and may thus represent a safe, natural treatment for AD."

Reference:

"Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease," Parachikova A, Green KN, et al, PLoS One, 2010 Nov 17; 5(11): e14015. (Address: Department of Neurobiology and Behavior, Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, California, United States of America).

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