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Nattokinase with Red Yeast Rice Benefits Blood Lipids in Patients with Hyperlipidemia

In a randomized, double-blind, placebo-controlled, parallel comparison study involving 47 patients with hyperlipidemia, supplementation with nattokinase (50 mg per capsule, twice daily dose of 2 capsules) along with red yeast rice (300 mg per capsule, twice daily dose of 2 capsules) was found to significantly reduce triglycerides by 15%, total cholesterol by 25%, LDL cholesterol by 41%, TC/HDL-cholesterol by 29.5%, and increase HDL cholesterol by 7.5% - as compared to subjects who received supplementation with nattokinase alone or a placebo. After controlling for baseline levels, as compared to those who received a placebo, subjects who received the combination of nattokinase and red yeast rice were found to have significant improvements in total cholesterol, LDL-cholesterol, and the TC/HDL-cholesterol ratio.
 
Reference:
“Combined nattokinase with red yeast rice but not nattokinase alone has potent effects on blood lipids in human subjects with hyperlipidemia,” Yang NC, Chou CW, et al, Asia Pac J Clin Nutr, 2009; 18(3): 310-7.
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Contributor Since:
June 19, 2008
Derrick DeSilva Jr., M.D.
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Dr. Derrick DeSilva is on the Attending Staff at the Raritan Bay Medical Center in Perth Amboy, N.J., and on the teaching faculty at JFK Medical Center in Edison, N.J.

He has lectured on various topics in medicine --nationally and internationally-- and has his own talk show called Ask the Doctor which airs on WCTC in New Jersey (1450 AM) as well as his own television show, "To Your ...