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Multivitamins and Micronutrients Including Coenzyme Q10 Supplementation Improve Semen Parameters in Azoospermic Patients

In a study involving 35 azoospermic patients with maturation arrest on testicular biopsy, treatment with multivitamins, micronutrients, and coenzyme Q10 (n=24) was found to improve sperm count, motility, and normal morphology, as compared to subjects who were untreated (n=11). Specifically, the treatment group was found to have reduction in liquefaction time and relative viscosity of the semen, Moreover, the appearance of spermatozoa (4.0 million/ml) exhibiting progressive motility (7%), and normal morphology (6%) was found in the treatment group. Within 3 months, 2 pregnancies were reported from people in the treatment group. Based on these results, the authors conclude that, "multivitamin and micronutrient supplementation improve the qualitative and quantitative parameters of seminogram in patients with azoospermia of maturation arrest."


"Multivitamin and micronutrient treatment improves semen parameters of azoospermic patients with maturation arrest," Singh AK, Tiwari AK, et al, Indian J Physiol Pharmacol, 2010 April-June; 54(2): 157-63. (Address: Department of Physiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi).

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Comments (1)

January 22, 2012 10:49 pm
This is a very interesting study! My husband had a testicular biopsy last year and was diagnosed with azoospermia due to sperm maturation arrest, and all of his hormone levels fall within normal ranges (FSH, Testosterone, etc...). So it seems to me that he would be in the same category as these patients. My question is can I buy a fertility multivitamin that contains all of these vitamins and nutrients? What would you recommend? Somehow we do have a naturally conceived son who was born prior to us learning about my husband\'s 0 sperm count. So this study really gives me hope that we can someday give him a brother or a sister. Thanks for the information.

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