Alternative Health Blog
Selenium, Folate, and Colon Cancer
In a large, population-based, case-control study involving 1,691 subjects with colon cancer, subjects with high serum selenium (>140 mcg/l) and high reported folate intake (>354 mcg/d) were found to have a reduced relative risk of colon cancer (OR=0.5). Subjects with high serum selenium but low folate intake did not have a reduced risk (OR=1.1), nor did those with low serum selenium and high folate (OR=0.9) - risk was comparable to those with low serum selenium and low folate. The authors conclude, “High levels of serum selenium and reported folate jointly were associated with a substantially reduced risk of colon cancer
Reference:
“Selenium, folate, and colon cancer,” Connelly-Frost A, Poole C, et al, Nutr Cancer, 2009; 61(2): 165-78.
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Dr. Derrick DeSilva is on the Attending Staff at the Raritan Bay Medical Center in Perth Amboy, N.J., and on the teaching faculty at JFK Medical Center in Edison, N.J.
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