| In a randomized, double-blind, placebo-controlled study involving 52 normomagnesemic, overweight, insulin resistant, non-diabetic subjects, results indicate that supplementation with magnesium may improve insulin sensitivity. The subjects were randomized to magnesium-aspartate-hydrochloride or placebo for 6 months. At intervention end, significant improvement in fasting glucose and some insulin sensitivity indices were observed in the magnesium group. Thus, the authors of this study conclude, "The results provide significant evidence that oral Mg supplementation improves insulin sensitivity even in normomagnesemic, overweight, non-diabetic subjects emphasizing the need for an early optimisation of Mg status to prevent insulin resistance and subsequently type 2 diabetes." | Reference: | "Oral magnesium supplementation reduces insulin resistance in non-diabetic subjects - a double-blind, placebo-controlled, randomized trial," Mooren FC, Kraus A, et al, Diabetes Obes Metab, 2010, Nov 18; [Epub ahead of print]. (Address: Department of Sports Medicine, Institute of Sports Sciences, Justus-Liebig-University, Kugelberg 62, Giessen 35394, Germany). | |