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Magnesium Supplementation May Help Prevent Migraine Headaches

In a randomized, double-blind, placebo-controlled study involving 40 patients with migraine headaches (with aura), supplementation with magnesium (600 mg/d) for a period of 3 months was found to reduce the frequency, severity, and P1 amplitude in visual evoked potential examination. In addition, those treated with magnesium were found to have reductions in post/pre-treatment ratios of migraine attack frequency, severity, and P1 amplitude. Significant increases in cortical blood flow in inferolateral frontal, inferolateral temporal, and insular regions were found after magnesium treatment. The authors conclude, “These results have made us think that magnesium is a beneficial agent in prophylaxis of migraine without aura and might work with both vascular and neurogenic mechanisms.”
 
Reference:
“The effects of magnesium prophylaxis in migraine without aura,” Koseoglu E, Talaslioglu A, et al, Magnes Res, 2009; 21(2): 101-
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Contributor Since:
June 19, 2008
Derrick DeSilva Jr., M.D.
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Dr. Derrick DeSilva is on the Attending Staff at the Raritan Bay Medical Center in Perth Amboy, N.J., and on the teaching faculty at JFK Medical Center in Edison, N.J.

He has lectured o...