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Low Vitamin D Status in Older Women Linked to Increased Mortality

In a prospective, population-based study involving 714 community-dwelling women between the ages of 70 and 79 years, low vitamin D status was found to be associated with an increased risk of mortality. During a median follow up of 72 months, during which time 14% (n=100) of the women died, women in the lowest quartile of 25(OH)D (<15.3 ng/mL) were found to have the highest risk of mortality (HR=2.45), as compared to women in the highest quartile (>27.0 ng/mL). These results suggest that older women with low vitamin D status have an increased risk of death. Additional research is needed to assess the effects of supplementation with vitamin D on mortality in this population
 
Reference:
“Low serum 25-hydroxyvitamin D concentrations are associated with greater all-cause mortality in older community-dwelling women,” Semba RD, Houston DK, et al, Nutr Metab, 2009; 29(8): 525-530. (Address: Department of Ophthalmology and the Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, MD 21287, USA).
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Contributor Since:
June 19, 2008
Derrick DeSilva Jr., M.D.
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Dr. Derrick DeSilva is on the Attending Staff at the Raritan Bay Medical Center in Perth Amboy, N.J., and on the teaching faculty at JFK Medical Center in Edison, N.J.

He has lectured o...