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Low Vitamin D Levels Linked to Increased Mortality Risk in Hemodialysis Patients

In a study involving 102 hemodialysis patients (57 male, 45 female, mean age: 60.5 years), subjects with 25(OH)D levels < or = 50 nmol/L were found to have significantly higher mortality rates than those with 25(OH)D levels above 50 nmol/L, according to Kaplan-Meier survival analysis. According to Cox multivariable regression modeling, the PTH level was found to be a predictor of mortality in this patient group. The study population as a whole was found to have vitamin D insufficiency. These results suggest that low vitamin D status may increase mortality in hemodialysis patients.

Reference:
"Vitamin D as a novel nontraditional risk factor for mortality in hemodialysis patients," Pecovnik-Balon B, Jakopin E, et al, There Apher Dial, 2009; 13(4): 268-72. (Address: Department of Nephrology, University Clinical Center Maribor, Maribor, Slovenia).
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Contributor Since:
June 19, 2008
Derrick DeSilva Jr., M.D.
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Dr. Derrick DeSilva is on the Attending Staff at the Raritan Bay Medical Center in Perth Amboy, N.J., and on the teaching faculty at JFK Medical Center in Edison, N.J.

He has lectured o...