Alternative Health Blog

In a placebo-controlled, single-blind study involving 24 men with mild ED (erectile dysfunction), results indicate that supplementation with L-citrulline may improve erectile hardness. The men were randomized to placebo or L-citrulline (1.5 g/d) for 1 month each. Erectile hardness score improved from 3 to 4 in 2% of subjects in the placebo group, compared with 50% of subjects in the L-citrulline group. Additionally, the mean number of intercourses per month increased in the L-citrulline group. Thus, the authors of this study conclude, "Although less effective than phosphodiesterase type-5 enzyme inhibitors, at least in the short term, L-citrulline supplementation has been proved to be safe and psychologically well accepted by patients. Its role as an alternative treatment for mild to moderate ED, particularly in patients with a psychologically fear of phosphodiesterase type-5 enzyme inhibitors, deserves further research."