In a study involving data collected from 57,053 healthy subjects, higher dietary intake of omega-3 fatty acids (including EPA, DHA, and DPA) was found to be associated with a lower incidence of acute coronary syndrome. Subjects were followed up with for 7.6 years, during which time 1,150 received a diagnosis of acute coronary syndrome. Subjects with higher omega-3 PUFA intake (>0.39 g/d) were found to have a lower hazard ratio (0.83) for acute coronary syndrome, as compared to men with lower intakes. These results suggest that increasing intakes of EPA, DHA, and DPA may help reduce the risk of acute coronary syndrome in healthy male adults.
“Dietary intake of total marine n-3 polyunsaturated fatty acids, eicosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid and the risk of acute coronary syndrome - a cohort study,” Joensen AM, Schmidt EB, et al, Br J Nutr, 2009; 14:1-6.