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Fish Oil Omega-3 Fatty Acids May Reduce Psychological Distress and Depressive Symptoms in Menopausal Women

In a randomized, placebo-controlled study involving 120 middle-aged women with moderate-to-severe psychological distress, supplementation with 1.05 g/d ethyl-eicosapentaenoic acid (E-EPA) plus 0.15 g/d ethyl-docosahexaenoic acid for a period of 8 weeks was found to improve depressive symptoms in patients without the diagnosis of major depressive episode at baseline. Improvements in the "Psychological General Well-Being Scale," the "Hopkins Symptom Checklist Depression Scale," and the "21-item Hamilton Depression Rating Scale" were found among patients taking the supplement. These results suggest that middle-aged women going through the menopausal transition, who experience psychological distress but not major depression may benefit from supplementation with E-EPA.
 
Reference:
"Ethyl-eicosapentaenoic acid for the treatment of psychological distress and depressive symptoms in middle-aged women: a double-blind, placebo-controlled, randomized clinical trial," Lucas M, Asselin G, et al, Am J Clin Nutr, 2008 Dec 20;
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June 19, 2008
Derrick DeSilva Jr., M.D.
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Dr. Derrick DeSilva is on the Attending Staff at the Raritan Bay Medical Center in Perth Amboy, N.J., and on the teaching faculty at JFK Medical Center in Edison, N.J.

He has lectured on various topics in medicine --nationally and internationally-- and has his own talk show called Ask the Doctor which airs on WCTC in New Jersey (1450 AM) as well as his own television show, "To Your ...