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Dry Eye and Essential Fatty Acids

In a literature review of studies examining the effects of essential fatty acids in patients with dry eye syndrome, based on the evidence reviewed, the authors conclude, “...Supplementation with omega-3 EFA may be beneficial in the treatment and prevention of DES.” The authors searched PubMed, ScienceDirect, and Ovid databases to identify relevant studies for review. Based on the studies identified and analyzed, the authors found that omega-3 and omega-6 fatty acids need to be consumed together within a reasonable ratio to be effective. The authors discuss the anti-inflammatory effects of omega-3 fatty acids “in the lacrimal gland preventing apoptosis of the secretory epithelial cells.” They go on, “Supplementation clears meibomitis, allowing a thinner, more elastic lipid layer to protect the tear film and cornea.” Based on the evidence identified and reviewed, the authors conclude that patients with dry eye syndrome may benefit from supplementation with omega-3 fatty acids.
 
Reference:
“Essential fatty acids for dry eye: A review,” Roncone M, Bartlett H, et al, Cont Lens Anterior Eye, 2009 Dec 21.
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Contributor Since:
June 19, 2008
Derrick DeSilva Jr., M.D.
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Dr. Derrick DeSilva is on the Attending Staff at the Raritan Bay Medical Center in Perth Amboy, N.J., and on the teaching faculty at JFK Medical Center in Edison, N.J.

He has lectured o...