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Decreased Levels of Coenzyme Q10 Found in Patients with Chronic Obstructive Pulmonary Disease (COPD)
By Derrick DeSilva Jr., M.D., Community Insider -- Published: December 23, 2010

In a study involving 45 patients with COPD acute exacerbation and 45 healthy smokers who served as a control group, levels of coenzyme Q10 and the copper/zinc ratio was significantly lower in the patient group than the control group. In addition, the patient group was found to have lower forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) and higher C-reactive protein, white blood cell count, and sedimentation rate. The authors conclude, "The decrease in CoQ10 level and Cu/Zn ratio and elevation in Cu and Zn levels observed in the patients probably result from the defense response of organism and are mediated by inflammatory-like substances."

Reference:

"Coenzyme Q10, Copper, Zinc, and Lipid Peroxidation Levels in Serum of Patients with Chronic Obstructive Pulmonary Disease," Tanrikulu AC, Abakay A, et al, Biol Trace Elem Res, 2010 Nov 16; [Epub ahead of print]. (Address: Department of Chest Disease, Medical Faculty, Dicle University, Diyarbakir, Turkey. E-mail: cetintanrikulu@hotmail.com ).
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