Alternative Health Blog

Curcumin for the Prevention of Colorectal Neoplasia

By Derrick DeSilva Jr., M.D., Community Insider -- Published: March 25, 2011

In a non-randomized, open-label, clinical trial involving 44 smokers with 8 or more ACF (aberrant crypt foci) on screening colonoscopy, administration of a 4 g dose of curcumin was found to be associated with a significant 40% reduction in ACF number, which was associated with significant, five-fold increase in post-treatment plasma curcumin/conjugate levels. A 2 g dose of curcumin did not yield such benefits. The authors conclude, "Our data suggest that curcumin can decrease ACF number, and this is potentially mediated by curcumin conjugates delivered systemically."

Reference:

"Phase IIa Clinical Trial of Curcumin for the Prevention of Colorectal Neoplasia," Carroll RE, Benya RV, et al, Cancer Prev Res (Phila), 2011 March; 4(3): 354-64. (Address: Department of Medicine, University of Illinois at Chicago, 840 South Wood Street (M/C 787), Chicago, IL 60612, USA. E-mail: rcarroll@uic.edu ).

Enter your Comment and click the "Submit" Button:

Comments

Add Comment

No Comments Currently

<< Older | Newer >>

Recent Blog Posts

Blog Archives

Disclaimer: Information on this site is provided for informational purposes only. It is not meant as a substitute for medical advice provided by your physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disease, or prescribing any medication. You should read carefully all product packaging and labels. If you have or suspect that you have a medical problem, promptly contact your physician or health care provider. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.