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Curcumin and Green Tea Catechins in Combination May Help Prevent Colon Cancer

In an animal study involving male Wistar rats, treatment with curcumin and green tea catechins, individually and in combination, was found to significantly reduce the incidence of colorectal cancer (reduction in total number of colorectal aberrant crypt foci, increased apoptotic index, decreased proliferation index), as compared to rats in a control group who did not receive the treatment. Treatment with the combination of curcumin and green tea catechins was found to exert the most potent inhibitory effect. The authors conclude, “Our findings suggest that the combination of curcumin and catechins may produce a synergistic colon cancer-preventative effect that would be more potent than each of the compounds alone.”
 
Reference:
“Combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis,” Xu G, Ren G, et al, Food Chem Toxicol, 2009 Oct 24
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