Alternative Health Blog

Coenzyme Q10 and Cognitive Function

By Derrick DeSilva Jr., M.D., Community Insider -- Published: July 03, 2011

In a placebo-controlled study involving 6 aged beagles (>8 years) who were treated with 80 mg/d atorvastatin (a statin drug) for 14.5 months, serum coenzyme Q10 levels were found to be lower in statin-treated drugs, as compared to those treated with a placebo. Moreover poorer cognition was found to be associated with lower levels of coenzyme Q10 in the lower parietal cortex. The authors conclude, "CoQ10 levels in brain may [be] linked to impaired cognition in response to atorvastatin, in agreement with previous reports that statins may have a negative impact on cognition in the elderly."

Reference:

"Coenzyme Q10 and cognition in atorvastatin treated dogs," Martin SB, Cenini G, et al, Neurosci Lett, 2011 July 8; [Epub ahead of print]. (Address: Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA).

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