Alternative Health Blog

Benefits of DHEA Supplementation in Women undergoing In Vitro Fertilization

By Derrick DeSilva Jr., M.D., Community Insider -- Published: May 03, 2011

In a case-control study involving 15 women with diminished ovarian reserve who were undergoing in vitro fertilization (IVF), supplementation with 75 mg/day DHEA (dehydroepiandrosterone) was found to be associated with significantly increased levels of progesterone on stimulation day 5 (0.58 ng/ml vs. 1.54 ng/ml) and on the day of human chorionic gonadotropin administration (0.75 ng/ml vs. 1.87 ng/ml). The number of retrieved and fertilized oocytes was similar between the 2 groups. The authors conclude, "DHEA administration during IVF cycles in women with DOR causes a significant elevation of progesterone levels without an apparent deleterious effect on cycle outcome."

Reference:

"Dehydroepiandrosterone supplementation increases baseline follicular phase progesterone levels," Weissman A, Horowitz E, et al, Gynecol Endocrinol, 2011 April 18; [Epub ahead of print]. (Address: Department of Obstetrics and Gynecology, IVF Unit, Edith Wolfson Medical Center, Holon, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel).

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