The Statin Drug-Cholesterol-CoQ10-Low Energy Controversy

A major controversy has developed in the USA and around the world over the possible excess use and adverse effects of statin drugs. 

INTRODUCTION
Statins are used to lower the production of cholesterols and in doing such reduce the build up of fatty deposits in blood vessels.  These cholesterol deposits have been clearly shown to be the major contributor to heart attack and stroke.  The adverse effects of the statin is an induced low energy syndrome caused by the statin inhibitor of the enzyme HMG-CoA reductase essential for the production of both cholesterol and coenzyme Q10 (CoQ10) (1).  CoQ10 is essential for energy synthesis in all the cells in the human body (2).  Thus, the induced low energy resulting from the reduction of the HMG-CoA reductase and therefore the reduced production of CoQ10 is the adverse side effect of the statin drugs that will greatly influence the quality of life and resistance to age related conditions in the aging American population. 

Today some 10 to12 million Americans are taking statin drugs for the control of LDL cholesterol.  The prevalence of coronary artery disease (CAD) is...